Autograft, allograft and regenten are three ways of treating a torn anterior cruciate ligament (ACL). Autograft involves taking a tendon from the patient’s body, whilst allograft involves a tendon taken from a donor. REGENTEN uses a collagen-based bioinductive implant.
2 minute check
A 2-minute, no-obligation check built on a clinically-validated knee screen. We'll estimate how likely an ACL injury is — and how much of your repair window is left.
A guided screening indicator based on a validated history questionnaire — not a diagnosis. Only an MRI reviewed by a specialist can confirm an ACL injury.
ACL reconstruction is a surgical procedure used to replace a torn anterior cruciate ligament and restore stability to the knee. The damaged ligament is removed and replaced using a graft, either from the patient’s own tissue (autograft), donor tissue (allograft), or enhanced biological scaffolds like REGENETEN. The graft integrates into the knee over time, forming a new ligament. It’s commonly performed arthroscopically, reducing recovery time and scarring.
Sports trauma: Quick pivots, stops, or directional changes during football, skiing, or basketball can tear the ACL.
Falls or collisions: Direct blows or awkward landings can overload and rupture the ligament.
Knee instability: Weak supporting muscles or past injuries can make the ACL more vulnerable.
Improper technique: Poor movement mechanics during training can increase strain on the knee.
Genetic or anatomical factors: Certain knee structures or limb alignments may predispose individuals to ACL damage.
Diagnosis typically begins with symptoms such as a popping sound at the time of injury, swelling, instability, and difficulty bearing weight. A physical exam includes specific tests to assess the integrity of the ACL, such as the Lachman or pivot shift test. MRI scans confirm the extent of ligament damage and help identify any associated injuries like meniscal tears. Surgery is usually recommended for active individuals or those with persistent instability after conservative treatment. Choosing between autograft, allograft, or regenerative options depends on patient needs, activity level, and recovery goals.
Who it suits
Autograft, allograft and REGENTEN similar treatments for ACL tear, each has slightly different benefits and possible side effects.
With allograft, a tendon is taken from a human cadaver, usually from the Achilles or patellar tendons. The donated tendon is thoroughly sterilised and processed before it is implanted into the patient’s knee.
With autograft, a tendon is harvested from the patient’s body. Tendons will usually be taken from the patellar, hamstring or quadriceps.
Cost and paying
We offer a range of flexible payment options to make your treatment experience smooth and stress-free.
Most patients choose to self-fund their treatment. We accept:
We’ve partnered with GoCardless to offer interest-free instalment options. You can easily set up a Direct Debit to spread the cost of your treatment over time.
Looking for a financing plan? You can apply through Kandoo, our trusted finance partner.
We work with a small number of approved insurance providers. However, due to restrictions from many insurers, not all treatments are covered. Please check with your insurer and speak to our team before booking to avoid disappointment.
What happens
Use our website to book an initial consultation, or give us a call.
Our doctors might request you arrange a scan before your initial consultation. Or, they’ll chat with you (face to face or online) and recommend a scan after your initial consultation, if they think you need one.
Once your scan results have been reviewed, and your doctor has explained your options, you will be booked in for treatment.
Following your treatment, your doctor will give you rehab recommendations.
You will be booked in for a follow-up consultation, so your doctor can check your progress. You might need further rehab after this consultation.
Once your doctor is happy with your recovery, you will be discharged. After discharge, we are always here for further questions or support, should you need it.
Are autograft, allograft and REGENTEN surgical procedures?
How long until I feel the results?
When comparing autograft and allograft, the recovery of autograft might be slightly faster in the short term. This is because the tendon often integrates faster. However, the long-term recovery is generally similar, with most patients returning to sport after 6-12 months.
Your specific recovery time will depend on individual factors like age, diet, activity level and your overall commitment to rehabilitation.
London Cartilage Clinic
We now offer select services at our Harley Street London clinic through the London Cartilage Clinic, led by internationally recognised surgeon Professor Paul Lee.
Our London clinic offers advanced treatments like cartilage regeneration and joint preservation to help patients avoid or delay joint replacement.
Located in Central London, our clinic provides convenient access to world-class musculoskeletal care without long NHS wait times.
If you would like to be seen in Central London, visit our London Clinic page for pricing, available treatments, and to book directly online.
Our Harley Street clinic uses cutting-edge techniques designed to reduce downtime and support faster, more effective recovery, getting you back to your lifestyle sooner.
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